Phenotypes Associated with This Genotype

Genotype
MGI:5487389

• Allelic Composition: Tph2^tm1Dmkh/Tph2^tm1Dmkh
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased core body temperature ( J:196205 )

• slightly

decreased serotonin level ( J:196205 )

• absent in the mesencephalic tegmentum, striatum, hippocampus, prefrontal cortex, hypothalamus and cerebellum

• however, serum levels are normal

nervous system

nervous system phenotype ( J:196205 )

N • mice exhibit normal methamphetamine-induced toxicity in the striatal dopamine nerve endings