Phenotypes for Mlana Tyr MGI:5484927 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mlana^tm1.2Bee/Mlana^tm1.2Bee Tyr^c/Tyr^c
Genetic Background	involves: 129S/SvEv * C57BL/6 * FVB/N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlana^tm1.2Bee mutation (1 available); any Mlana mutation (9 available)
Tyr^c mutation (79 available); any Tyr mutation (383 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal hair follicle melanocyte morphology ( J:194886 )

• hair follicles lack stage III and IV melanosomes

• however, stage I and II melanosomes are normal

absent skin pigmentation ( J:194886 )

integument

abnormal hair follicle melanocyte morphology ( J:194886 )

• hair follicles lack stage III and IV melanosomes

• however, stage I and II melanosomes are normal

absent skin pigmentation ( J:194886 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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