Phenotypes Associated with This Genotype

Genotype
MGI:5477810

• Allelic Composition: Rhbg^tm1.1Idw/Rhbg^tm1.1Idw; Tg(ATP6V1B1-cre)45Rnel/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:195261 )

N • no differences in titratable acid excretion, urine pH, urinary electrolyte excretion, serum bicarbonate levels, or serum potassium levels are detected under basal or acid loading conditions

decreased urine ammonia level ( J:195261 )

• following acid loading, urinary ammonia levels are reduced by about 25% compared to controls

• however, basal ammonia excretion is similar to controls

renal/urinary system

decreased urine ammonia level ( J:195261 )

• following acid loading, urinary ammonia levels are reduced by about 25% compared to controls

• however, basal ammonia excretion is similar to controls