Phenotypes for Tg(T-cre)1Lwd Zic3 MGI:5476844 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Zic3^tm1.1Smwa/Y Tg(T-cre)1Lwd/0
Genetic Background	involves: C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(T-cre)1Lwd mutation (1 available)
Zic3^tm1.1Smwa mutation (0 available); any Zic3 mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal left-right axis patterning ( J:194989 )

• at E8.5

abnormal primitive node morphology ( J:194989 )

• similar to germ line null mice

cardiovascular system

abnormal heart looping ( J:194989 )

• defects in looping similar to those in germ line null mice are seen at E10.5 and E13.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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