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Phenotypes Associated with This Genotype
Genotype
MGI:5476672
Allelic
Composition
Tg(Eno2-MFN2*R94Q)L51Ugfm/Tg(Eno2-MFN2*R94Q)L51Ugfm
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Eno2-MFN2*R94Q)L51Ugfm mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice exhibit normal cerebellum morphology
• at 12 months, the proportion of small and medium axons is increased while proportion of large axons is decreased compared to in control mice
• the component area to amplitude ratio generated by small-medium fibers Adelta is increased compared to in control nerves

behavior/neurological
• at 5 months with homogenous phenotype

cellular
• in medium and small myelinated axons at 12 months
• however, large axons exhibit normal numbers of mitochondria


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory