Phenotypes for Cd3e Nlrp1a MGI:5474289 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cd3e^tm1Mal/Cd3e^tm1Mal Nlrp1a^Neut1/Nlrp1a^Neut1
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd3e^tm1Mal mutation (4 available); any Cd3e mutation (47 available)
Nlrp1a^Neut1 mutation (0 available); any Nlrp1a mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased neutrophil cell number ( J:191055 )

skin inflammation ( J:191055 )

• neutrophil infiltration of the dermis

increased susceptibility to infection induced morbidity/mortality ( J:191055 )

• reduction in disease free survival

mortality/aging

increased susceptibility to infection induced morbidity/mortality ( J:191055 )

• reduction in disease free survival

hematopoietic system

increased neutrophil cell number ( J:191055 )

integument

skin inflammation ( J:191055 )

• neutrophil infiltration of the dermis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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