Phenotypes for Cfl1 Vangl2 MGI:5473706 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cfl1^tm1.2Wit/Cfl1^tm1.2Wit Vangl2^Lp/Vangl2^Lp
Genetic Background	involves: 129 * LPT/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfl1^tm1.2Wit mutation (0 available); any Cfl1 mutation (25 available)
Vangl2^Lp mutation (2 available); any Vangl2 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:194042 )

• arrest at approximately E9.5

embryo

abnormal embryo turning ( J:194042 )

• fail to undergo turning

embryonic growth arrest ( J:194042 )

• at approximately E9.5

decreased embryo size ( J:194042 )

• shorter at E9.5

open neural tube ( J:194042 )

• open along the entire axis of the embryo at E9.5

abnormal somite development ( J:194042 )

growth/size/body

decreased embryo size ( J:194042 )

• shorter at E9.5

nervous system

open neural tube ( J:194042 )

• open along the entire axis of the embryo at E9.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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