Phenotypes Associated with This Genotype

Genotype
MGI:5473607

• Allelic Composition: Frem1^eyes2/Frem1^eyes2
• Genetic Background: C57BL/6J-Frem1^eyes2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

diaphragmatic hernia ( J:192553 )

• in the anterior midline directly behind the sternum 6 of 73 mice

renal/urinary system

single kidney ( J:192553 )

• in 9 of 73 mice

vision/eye

abnormal eye morphology ( J:192553 )

• in 62 of 73 mice

eyelids fail to open ( J:89098 )

• affected mice are described as having closed eyes

respiratory system

fused right lung lobes ( J:200175 )

• the cranial, medial, and caudal lobes of the right lung are partially or completely fused in 55/73 affected mice

digestive/alimentary system

abnormal anogenital distance ( J:200175 )

♂ • males exhibit a decreased anogenital distance

reproductive system

abnormal anogenital distance ( J:200175 )

♂ • males exhibit a decreased anogenital distance

growth/size/body

abnormal postnatal growth/weight/body size ( J:89098 )

• affected mice are described as being generally less fit than littermates