Phenotypes for Apoe Ptgdr MGI:5473362 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apoe^tm1Unc/Apoe^tm1Unc Ptgdr^tm1Dgen/Ptgdr^tm1Dgen
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoe^tm1Unc mutation (35 available); any Apoe mutation (164 available)
Ptgdr^tm1Dgen mutation (0 available); any Ptgdr mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating triglyceride level ( J:192168 )

• in 1 of 2 studies of mice fed a high fat diet

increased cholesterol level ( J:192168 )

• modest in the aorta at 16 and 24, but not 32, weeks in mice fed a high fat diet

increased circulating cholesterol level ( J:192168 )

• in some mice fed a high fat diet

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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