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Phenotypes Associated with This Genotype
Genotype
MGI:5471826
Allelic
Composition		 Wnt1tm1Brd/Wnt1tm1Brd
Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt1tm1Brd mutation (0 available); any Wnt1 mutation (29 available)
Wnt8atm1(KOMP)Vlcg mutation (1 available); any Wnt8a mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal endolymphatic duct morphology ( J:194132 )
• reduced endolymphatic sac at the dorsal portion of the endolymphatic duct at E15.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory