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Phenotypes Associated with This Genotype
Genotype
MGI:5471140
Allelic
Composition
Gpsm1tm1.1Lajb/Gpsm1+
Pkd1tm1.1Fqi/Pkd1tm1.1Fqi
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpsm1tm1.1Lajb mutation (1 available); any Gpsm1 mutation (45 available)
Pkd1tm1.1Fqi mutation (0 available); any Pkd1 mutation (153 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• blood urea nitrogen is higher than in wild-type mice but is increased to a similar extent as in single Pkd1 homozygotes

renal/urinary system
• kidney-to-body weight ratio is higher at P11-12 than in wild-type mice but similar to that in single Pkd1 homozygotes

growth/size/body
• kidney-to-body weight ratio is higher at P11-12 than in wild-type mice but similar to that in single Pkd1 homozygotes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory