Phenotypes Associated with This Genotype

Genotype
MGI:5470526

• Allelic Composition: B4gat1^m1Ddg/B4gat1^m1Ddg
• Genetic Background: involves: C3H/He * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon fasciculation ( J:194150 )

• axons emanating from the midbrain and cranial nerves are truncated and defasciculated at the level of the vagal complex compared with wild-type mice

• mice exhibit defects (highly defasciculated, patchy and discontinuous) in the formation of the dorsal funiculus by the central projections of the dorsal root ganglia sensory neurons compared with wild-type mice

abnormal axon guidance ( J:194150 )

• axons emanating from the midbrain and cranial nerves are truncated and defasciculated at the level of the vagal complex compared with wild-type mice

abnormal nervous system tract morphology ( J:194150 )

• axons emanating from the midbrain and cranial nerves are truncated and defasciculated at the level of the vagal complex compared with wild-type mice

abnormal spinal cord dorsal column morphology ( J:194150 )

• mice exhibit defects (highly defasciculated, patchy and discontinuous) in the formation of the dorsal funiculus by the central projections of the dorsal root ganglia sensory neurons compared with wild-type mice

muscle

dystrophic muscle ( J:194150 )

• mild with variable penetrance

cellular

abnormal axon fasciculation ( J:194150 )

• axons emanating from the midbrain and cranial nerves are truncated and defasciculated at the level of the vagal complex compared with wild-type mice

• mice exhibit defects (highly defasciculated, patchy and discontinuous) in the formation of the dorsal funiculus by the central projections of the dorsal root ganglia sensory neurons compared with wild-type mice

abnormal axon guidance ( J:194150 )

• axons emanating from the midbrain and cranial nerves are truncated and defasciculated at the level of the vagal complex compared with wild-type mice