About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5468352
Allelic
Composition		 Ccnd1tm1Wbg/Ccnd1tm5.1Pisc
Tg(CAG-cre/Esr1*)5Amc/0
Tg(MMTV-Erbb2)NK1Mul/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnd1tm1Wbg mutation (2 available); any Ccnd1 mutation (23 available)
Ccnd1tm5.1Pisc mutation (1 available); any Ccnd1 mutation (23 available)
Tg(CAG-cre/Esr1*)5Amc mutation (11 available)
Tg(MMTV-Erbb2)NK1Mul mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
abnormal tumor progression ( J:192032 )
• tamoxifen-treatment halts cancer progression and lowers tumor burden with increased senescence of tumor cells compared to in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory