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Phenotypes Associated with This Genotype
Genotype
MGI:5468139
Allelic
Composition		 Cd247tm2.1Lov/Cd247tm2.1Lov
Tg(TcraH-Y,TcrbH-Y)71Vbo/0
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd247tm2.1Lov mutation (0 available); any Cd247 mutation (12 available)
Tg(TcraH-Y,TcrbH-Y)71Vbo mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell differentiation ( J:192915 )
• thymocyte negative selection in response to ubiquitous male antigen is impaired, but not abrogated, compared to in control mice

immune system
abnormal T cell differentiation ( J:192915 )
• thymocyte negative selection in response to ubiquitous male antigen is impaired, but not abrogated, compared to in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory