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Phenotypes Associated with This Genotype
Genotype
MGI:5467841
Allelic
Composition		 Mirc14tm1.1Czc/Mirc14tm1.1Czc
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Genetic
Background		 either: (involves: 129P2/OlaHsd * 129S4/SvJae * 129S4/SvJaeSor) or (involves: 129P2/OlaHsd * 129S4/SvJae * 129S4/SvJaeSor * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT2)Tyj mutation (7 available); any Gt(ROSA)26Sor mutation (1098 available)
Mirc14tm1.1Czc mutation (1 available); any Mirc14 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
thymus hypoplasia ( J:188125 )
• in tamoxifen-treated mice
decreased double-positive T cell number ( J:188125 )
• in tamoxifen-treated mice

hematopoietic system
thymus hypoplasia ( J:188125 )
• in tamoxifen-treated mice
decreased double-positive T cell number ( J:188125 )
• in tamoxifen-treated mice

endocrine/exocrine glands
thymus hypoplasia ( J:188125 )
• in tamoxifen-treated mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory