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Phenotypes Associated with This Genotype
Genotype
MGI:5464109
Allelic
Composition
tw5/tw5
Vps52t-w5/Vps52t-w5
Genetic
Background
B6.Cg-tw5
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
tw5 mutation (3 available); any t mutation (19 available)
Vps52t-w5 mutation (0 available); any Vps52 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• the epithelial layer of the embryonic ectoderm fails to form by E6.5
• cell proliferation is very low in the embryonic ectoderm
• however, formation of extraembryonic tissues is similar to controls
• absence of cavitation in embryonic tissues; however, cavitation is seen in extraembryonic tissues

growth/size/body


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory