Phenotypes for Fcgr2b Traf3ip2 MGI:5462356 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Traf3ip2^tm2Sbn/Traf3ip2⁺
Genetic Background	involves: 129S4/SvJae * BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcgr2b^tm1Ttk mutation (7 available); any Fcgr2b mutation (49 available)
Traf3ip2^tm2Sbn mutation (0 available); any Traf3ip2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

enlarged spleen ( J:191090 )

increased spleen weight ( J:191090 )

spleen hyperplasia ( J:191090 )

increased germinal center B cell number ( J:191090 )

• increase in the total number of germinal center B cells

increased plasma cell number ( J:191090 )

• increase in the percentage and number of plasma cells

immune system

enlarged spleen ( J:191090 )

increased spleen weight ( J:191090 )

spleen hyperplasia ( J:191090 )

increased germinal center B cell number ( J:191090 )

• increase in the total number of germinal center B cells

increased plasma cell number ( J:191090 )

• increase in the percentage and number of plasma cells

growth/size/body

enlarged spleen ( J:191090 )

increased spleen weight ( J:191090 )

spleen hyperplasia ( J:191090 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24