Phenotypes for Apoe Thbd MGI:5462232 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Apoe^tm1Unc/Apoe^tm1Unc Thbd^{tm1.1(THBD)Sltz}/Thbd^{tm1.1(THBD)Sltz}
Genetic Background	B6.129(FVB)-Thbd^{tm1.1(THBD)Sltz} Apoe^tm1Unc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoe^tm1Unc mutation (34 available); any Apoe mutation (163 available)
Thbd^{tm1.1(THBD)Sltz} mutation (0 available); any Thbd mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:191461 )

N	• mice fed a high fat diet exhibit the same increase in total cholesterol, atherosclerotic lesion area and time to occlusion of the carotid artery following photochemical injury as Apoe^tm1Unc homozygotes

abnormal enzyme/coenzyme activity ( J:191461 )

• mice fed a high fat diet exhibit decreased amount of circulating activated protein C compared with Apoe^tm1Unc homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24