About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5451045
Allelic
Composition		 Apoetm1Unc/Apoetm1Unc
Dp(17Nfkbil1-Or2h1)1Cogr/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (34 available); any Apoe mutation (163 available)
Dp(17Nfkbil1-Or2h1)1Cogr mutation (1 available); any Dp(17Nfkbil1-Or2h1)1Cogr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Decreased susceptibility to atherosclerosis in Apoetm1Unc/Apoetm1Unc Dp(17Nfkbil1-Or2h1)1Cogr/0 mice

cardiovascular system
decreased susceptibility to atherosclerosis ( J:190754 )
• mice fed a high fat diet develop smaller plaques than in Apoetm1Unc homozygotes

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:190754 )
N
• mice fed a high fat diet exhibit the same cholesterol and glucose serum levels and glucose tolerance as Apoetm1Unc homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory