mortality/aging
• adults injected with adenoassociated virus expressing Cre-GFP to selectively inactive Ndufs4 in the vestibular nucleus exhibit increased mortality
|
growth/size/body
weight loss
(
J:190475
)
• adults injected with a Cre-expressing adenoassociated virus exhibit weight loss
|
nervous system
microgliosis
(
J:190475
)
• adults injected with a Cre-expressing adenoassociated virus develop extensive microglial activation one month after injection
|
respiratory system
• adults injected with a Cre-expressing adenoassociated virus exhibit more irregular breathing than controls and occasional gasping as behavior deteriorates
|
• adults injected with a Cre-expressing adenoassociated virus exhibit a normal response to hypoxia but a blunted hypercapnic ventilator response
|
behavior/neurological
• adults injected with a Cre-expressing adenoassociated virus exhibit motor coordination deficits on the rotorod
|
hematopoietic system
microgliosis
(
J:190475
)
• adults injected with a Cre-expressing adenoassociated virus develop extensive microglial activation one month after injection
|
immune system
microgliosis
(
J:190475
)
• adults injected with a Cre-expressing adenoassociated virus develop extensive microglial activation one month after injection
|