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Phenotypes Associated with This Genotype
Genotype
MGI:5451015
Allelic
Composition		 Abca1tm1Jdm/Abca1tm1Jdm
Abcg1tm1Dgen/Abcg1tm1Dgen
Apoetm1Unc/Apoetm1Unc
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * DBA * DBA/1LacJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abca1tm1Jdm mutation (1 available); any Abca1 mutation (88 available)
Abcg1tm1Dgen mutation (0 available); any Abcg1 mutation (45 available)
Apoetm1Unc mutation (34 available); any Apoe mutation (163 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal hematopoietic system physiology ( J:190966 )
• mice fed a high fat diet exhibit increased hematopoietic stem and multipotential progenitor cell (HSPC) mobilization compared with wild-type mice
• however, treatment with recombinant HDL suppresses this increase

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory