About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5449895
Allelic
Composition
Tg(SOD1*L126Z)#Deng/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• lifespan is on average 359 days (J:109458)
• lifespan is on average 359 days (J:109458)

nervous system
• mutants exhibit extensive protein aggregates of the mutant protein in the gray matter of the spinal cord at 350 days of age (J:109458)
• mutants exhibit extensive protein aggregates of the mutant protein in the gray matter of the spinal cord at 350 days of age (J:109458)
• mutants develop an amyotrophic lateral sclerosis-like phenotype by the age of 300-400 days, with an average onset of 336.3 days (J:109458)
• mutants develop an amyotrophic lateral sclerosis-like phenotype by the age of 300-400 days, with an average onset of 336.3 days (J:109458)

Mouse Models of Human Disease
OMIM ID Ref(s)
Amyotrophic Lateral Sclerosis 1; ALS1 105400 J:109458


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory