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Phenotypes Associated with This Genotype
Genotype
MGI:5447540
Allelic
Composition		 Nr3c1tm1.1Jda/Nr3c1+
Tg(Lck-cre)548Jxm/0
Genetic
Background		 B6.Cg-Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr3c1tm1.1Jda mutation (1 available); any Nr3c1 mutation (36 available)
Tg(Lck-cre)548Jxm mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte apoptosis ( J:189951 )
• thymocytes are less sensitive to dexamethasone-induced apoptosis compared with wild-type cells

cellular
decreased thymocyte apoptosis ( J:189951 )
• thymocytes are less sensitive to dexamethasone-induced apoptosis compared with wild-type cells

hematopoietic system
decreased thymocyte apoptosis ( J:189951 )
• thymocytes are less sensitive to dexamethasone-induced apoptosis compared with wild-type cells

endocrine/exocrine glands
decreased thymocyte apoptosis ( J:189951 )
• thymocytes are less sensitive to dexamethasone-induced apoptosis compared with wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory