Phenotypes for Rb1 Trim27 MGI:5446920 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rb1^tm1Tyj/Rb1⁺ Trim27^{Gt(XP0484)Wtsi}/Trim27^{Gt(XP0484)Wtsi}
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1^tm1Tyj mutation (4 available); any Rb1 mutation (116 available)
Trim27^{Gt(XP0484)Wtsi} mutation (0 available); any Trim27 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor incidence ( J:189317 )

• as in Rb1^tm1Tyj heterozygotes

increased pituitary gland tumor incidence ( J:189317 )

• as in Rb1^tm1Tyj heterozygotes

increased thyroid tumor incidence ( J:189317 )

• as in Rb1^tm1Tyj heterozygotes

endocrine/exocrine glands

increased pituitary gland tumor incidence ( J:189317 )

• as in Rb1^tm1Tyj heterozygotes

increased thyroid tumor incidence ( J:189317 )

• as in Rb1^tm1Tyj heterozygotes

nervous system

increased pituitary gland tumor incidence ( J:189317 )

• as in Rb1^tm1Tyj heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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