Phenotypes for Rb1 Trim27 MGI:5446919 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rb1^tm1Tyj/Rb1^tm1Tyj Trim27^{Gt(XP0484)Wtsi}/Trim27^{Gt(XP0484)Wtsi}
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1^tm1Tyj mutation (5 available); any Rb1 mutation (117 available)
Trim27^{Gt(XP0484)Wtsi} mutation (0 available); any Trim27 mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

increased cell proliferation ( J:189317 )

• under a 3T3 protocol, mouse embryonic fibroblasts exhibit increased cell proliferation compared with cells from Trim27^{Gt(XP0484)Wtsi} homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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