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Phenotypes Associated with This Genotype
Genotype
MGI:5446522
Allelic
Composition		 Zfhx3tm1.1Jtd/Zfhx3tm1.1Jtd
Tg(Pbsn-cre)4Prb/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Pbsn-cre)4Prb mutation (2 available)
Zfhx3tm1.1Jtd mutation (1 available); any Zfhx3 mutation (131 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
increased prostate intraepithelial neoplasia incidence ( J:189563 )
• in mice with cre-expression in the prostate

neoplasm
increased prostate intraepithelial neoplasia incidence ( J:189563 )
• in mice with cre-expression in the prostate

reproductive system
increased prostate intraepithelial neoplasia incidence ( J:189563 )
• in mice with cre-expression in the prostate

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory