Phenotypes Associated with This Genotype

Genotype
MGI:5446040

• Allelic Composition: Mex3c^{Gt(DD0642)Wtsi}/Mex3c^{Gt(DD0642)Wtsi}
• Genetic Background: B6.129P2-Mex3c^{Gt(DD0642)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:189503 )

• Background Sensitivity: more than 85% of mice on a C57BL/6 background die within hours of birth unlike mice on a mixed or congenic FVB background

respiratory system

abnormal pulmonary alveolus morphology ( J:189503 )

• poorly expanded alveolar space in neonates

homeostasis/metabolism

cyanosis ( J:189503 )

• in neonates

growth/size/body

postnatal growth retardation ( J:189503 )

• in mice that survive to adulthood