Phenotypes Associated with This Genotype

Genotype
MGI:5444859

• Allelic Composition: Grhl3^{tm2.1(F2rl1)Cgh}/Grhl3⁺
• Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * FVB/N)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

epidermal hyperplasia ( J:189278 )

• from two weeks onward

scaly skin ( J:189278 )

• although normal at birth, mice start to display scaly skin from 2 weeks onward

• most evident on the tail

skin lesions ( J:189278 )

• with occasional lymph node swelling

behavior/neurological

excessive scratching ( J:189278 )

• in adulthood but not in young mice

• not observed in mice without skin lesions and does not preceed the appearance of lesions