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Phenotypes Associated with This Genotype
Genotype
MGI:5444198
Allelic
Composition
Ppargtm2Rev/Ppargtm2Rev
Tg(Tagln-cre)1Her/?
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppargtm2Rev mutation (1 available); any Pparg mutation (23 available)
Tg(Tagln-cre)1Her mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• increased muscularization of pulmonary arteries at the alveolar wall
• elevated right ventricular systolic pressure

Mouse Models of Human Disease
OMIM ID Ref(s)
Pulmonary Hypertension, Primary, 1; PPH1 178600 J:136168


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory