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Phenotypes Associated with This Genotype
Genotype
MGI:5442377
Allelic
Composition		 Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Hnrnpltm1.1Tmo/Hnrnpltm1.1Tmo
Tg(Lck-cre)548Jxm/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1098 available)
Hnrnpltm1.1Tmo mutation (0 available); any Hnrnpl mutation (33 available)
Tg(Lck-cre)548Jxm mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell differentiation ( J:188749 )
• T cells either do not leave thymus or fail to migrate into the blood and to the peripheral lymphoid organs

hematopoietic system
abnormal T cell differentiation ( J:188749 )
• T cells either do not leave thymus or fail to migrate into the blood and to the peripheral lymphoid organs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory