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Phenotypes Associated with This Genotype
Genotype
MGI:5440902
Allelic
Composition
Wnt7apx-J/Wnt7apx-J
Genetic
Background
C57BL/6J-Wnt7apx-J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt7apx-J mutation (1 available); any Wnt7a mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• sperm appear sluggish but can be used successfully for in vitro fertilization

limbs/digits/tail
• all have missing or shortened digits of the front paws but only a few have missing digits of the hind paws
• the front limbs are malformed and shortened

reproductive system
• sperm appear sluggish but can be used successfully for in vitro fertilization
• although females are infertile they can be used successfully as ovarian transplant donors for reproduction

hearing/vestibular/ear
N
• auditory brainstem response is normal at 2 months of age

vision/eye

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Fuhrmann syndrome DOID:0090067 OMIM:228930
J:188477


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory