Phenotypes Associated with This Genotype

Genotype
MGI:5440892

• Allelic Composition: Tg(Cdh16-Wnk1*)#Cihu/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating aldosterone level ( J:168700 )

decreased circulating potassium level ( J:168700 )

increased circulating angiotensinogen level ( J:168700 )

increased urine potassium level ( J:168700 )

• in mice fed a normal sodium diet

increased urine sodium level ( J:168700 )

• during the first 7 days in mice fed a low sodium diet

cardiovascular system

decreased systemic arterial diastolic blood pressure ( J:168700 )

• in mice fed a normal sodium diet

decreased systemic arterial systolic blood pressure ( J:168700 )

• in mice fed a normal sodium diet

renal/urinary system

increased urine potassium level ( J:168700 )

• in mice fed a normal sodium diet

increased urine sodium level ( J:168700 )

• during the first 7 days in mice fed a low sodium diet