About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5440723
Allelic
Composition		 Setdb1tm1.1Yshk/Setdb1tm1.1Yshk
Tg(Nes-cre)1Kag/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setdb1tm1.1Yshk mutation (1 available); any Setdb1 mutation (60 available)
Tg(Nes-cre)1Kag mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:188109 )
• born alive but do not survive beyond P10

nervous system
abnormal astrocyte morphology ( J:188109 )
• increase in the number of astrocytes in the cortex at E18.5

cellular
abnormal astrocyte morphology ( J:188109 )
• increase in the number of astrocytes in the cortex at E18.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory