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Phenotypes Associated with This Genotype
Genotype
MGI:5440277
Allelic
Composition
F2rtm1Ajc/F2rtm1Ajc
F2rl1tm1Cgh/F2rl1tm1Cgh
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F2rl1tm1Cgh mutation (3 available); any F2rl1 mutation (60 available)
F2rtm1Ajc mutation (2 available); any F2r mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• neural tube defects are largely confined to the hindbrain region with only 5% showing involvement of the midbrain and none showing forebrain involvement
• defects generally only become obvious after E10.5
• occasional

nervous system
• neural tube defects are largely confined to the hindbrain region with only 5% showing involvement of the midbrain and none showing forebrain involvement
• defects generally only become obvious after E10.5
• occasional

limbs/digits/tail
• occasional


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory