Phenotypes for Prss8 Spint2 St14 MGI:5440275 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Prss8^fr/Prss8^fr Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14⁺
Genetic Background	involves: 129P2/OlaHsd * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prss8^fr mutation (13 available); any Prss8 mutation (22 available)
Spint2^{Gt(KST272)Byg} mutation (0 available); any Spint2 mutation (15 available)
St14^tm1Bug mutation (0 available); any St14 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:188121 )

N	• expected numbers are found at term unlike mutant mice wild-type for St14

embryo

embryo phenotype ( J:188121 )

N	• complete rescue of neural tube closure and placental differentiation defects seen in mice homozygous for Spint2^{Gt(KST272)Byg} and heterozygous Prss8^fr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24