Phenotypes for Ctnnb1 Gt(ROSA)26Sor Tg(Foxn1-cre)1Tbo MGI:5440184 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem}/Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem} Tg(Foxn1-cre)1Tbo/0
Genetic Background	involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2.1Kem mutation (0 available); any Ctnnb1 mutation (47 available)
Ctnnb1^tm2Kem mutation (1 available); any Ctnnb1 mutation (47 available)
Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem} mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Foxn1-cre)1Tbo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

integument phenotype ( J:187739 )

N	• skin lesions are not seen unlike in mutant mice lacking Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem}

sparse hair ( J:187739 )

• thinner but continuous coat

growth/size/body

decreased body size ( J:187739 )

• at P14; however, mice catch up with littermate controls with age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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