Phenotypes for Ctnnb1 Gt(ROSA)26Sor Tg(Cdx1-cre)23Kem MGI:5440180 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem}/Gt(ROSA)26Sor⁺ Tg(Cdx1-cre)23Kem/0
Genetic Background	involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2.1Kem mutation (0 available); any Ctnnb1 mutation (47 available)
Ctnnb1^tm2Kem mutation (1 available); any Ctnnb1 mutation (47 available)
Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem} mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Cdx1-cre)23Kem mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:187739 )

embryo

caudal body truncation ( J:187739 )

• at E14.5 embryos consist of a head attached to internal organs including lung, liver and intestine while the urogenital system and mesoderm-derived tissues making up the body wall are highly underdeveloped or absent

truncated tail bud ( J:187739 )

• truncated tail bud region at E9.5

limbs/digits/tail

truncated tail bud ( J:187739 )

• truncated tail bud region at E9.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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