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Phenotypes Associated with This Genotype
Genotype
MGI:5440069
Allelic
Composition
Braftm1Cpri/Braf+
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Braftm1Cpri mutation (0 available); any Braf mutation (58 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice infected with adenovirus cre exhibit increased incidence of lung tumors compared with Krastm4Tyj heterozygotes
• in mice infected with adenovirus cre

cellular
• primary mouse embryonic fibroblast treated with adenoviral-cre exhibit enhanced growth rate compared with wild-type cells

respiratory system
• mice infected with adenovirus cre exhibit increased incidence of lung tumors compared with Krastm4Tyj heterozygotes
• in mice infected with adenovirus cre


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory