Phenotypes for Dag1 Dmd MGI:5438997 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Dag1^tm1.1Swin/Dag1^tm1.1Swin Dmd^mdx/Dmd^mdx
Genetic Background	involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dag1^tm1.1Swin mutation (0 available); any Dag1 mutation (109 available)
Dmd^mdx mutation (30 available); any Dmd mutation (153 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating creatine kinase level ( J:187750 )

• less so than in Dmd^mdx homozygotes or hemizygotes

increased susceptibility to injury ( J:187750 )

• muscles exhibit partial protection against contraction-induced injury compared with Dmd^mdx homozygotes or hemizygotes

muscle

centrally nucleated skeletal muscle fibers ( J:187750 )

• less so than in Dmd^mdx homozygotes or hemizygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23