Phenotypes Associated with This Genotype

Genotype
MGI:5438794

• Allelic Composition: Tg(Camk2a-tTA)1Mmay/?
• Genetic Background: B6.Cg-Tg(Camk2a-tTA)1Mmay

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal long-term spatial reference memory ( J:185792 )

• mice swim less distance in the target quadrant than controls when tested for long-term recall suggesting a memory consolidation impairment

nervous system

nervous system phenotype ( J:185792 )

N • Background Sensitivity: no evidence of overt dentate degeneration on the C57BL/6 congenic background as compared to C3H/He and CBA genetic backgrounds

N • granule cell layer is similar to control at all time points studied