Phenotypes for Gt(ROSA)26Sor Tg(Pdx1-cre)89.1Dam MGI:5438294 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(Mir7-1,-EGFP)Horn}/Gt(ROSA)26Sor⁺ Tg(Pdx1-cre)89.1Dam/0
Genetic Background	involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(Mir7-1,-EGFP)Horn} mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
Tg(Pdx1-cre)89.1Dam mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

decreased glucagon secretion ( J:187631 )

• reduced immunohistochemistry at E15.5 in the pancreas

decreased insulin secretion ( J:187631 )

• reduced immunohistochemistry at E15.5 in the pancreas

homeostasis/metabolism

decreased glucagon secretion ( J:187631 )

• reduced immunohistochemistry at E15.5 in the pancreas

decreased insulin secretion ( J:187631 )

• reduced immunohistochemistry at E15.5 in the pancreas

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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