Analysis Tools
reproductive system
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• synaptonemal complexes fail to form central elements
• more numerous and abnormal chiasma-like structures form with conjoined or fused axes
• diplotene cells exhibit non-centromeric ends of the homolog axes fused to form contiguous terminal loops
• centromere pairing is reduced compared to in wild-type cells sister-chromatid individualization is exaggerated compared to in wild-type cells
• centromeric termini are more fragile and fractured in appearance compared to in wild-type cells
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