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Phenotypes Associated with This Genotype
Genotype
MGI:5435903
Allelic
Composition		 Il13tm1(YFP/cre)Lky/Il13+
Il4tm1(CD2)Mmrs/Il4+
Gt(ROSA)26Sortm1(DTA)Lky/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Lky mutation (3 available); any Gt(ROSA)26Sor mutation (944 available)
Il13tm1(YFP/cre)Lky mutation (1 available); any Il13 mutation (29 available)
Il4tm1(CD2)Mmrs mutation (0 available); any Il4 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased eosinophil cell number ( J:178986 )
• in the lungs of mice infected with N. brasiliensis
increased susceptibility to parasitic infection ( J:178986 )
• mice exhibit reduced helminthes Nippostrongylus brasiliensis expulsion compared with control mice

hematopoietic system
decreased eosinophil cell number ( J:178986 )
• in the lungs of mice infected with N. brasiliensis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory