Mouse Genome Informatics
cn
    Fktntm1Kcam/Fktntm1Kcam
Myf5tm3(cre)Sor/Myf5+

involves: 129S/SvEv * 129S4/SvJaeSor
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• 11% die before 20 weeks of age even with special feeding
• remainder are dead or euthanized by 35 weeks

growth/size/body
• significantly under weight
• combined gastrocnemius and soleus weight is low

muscle
• moderate to severe dystrophic features in the iliopsoas muscle at 20 weeks

homeostasis/metabolism
• elevated at 4 and 8 weeks

behavior/neurological
• forelimb grip strength is reduced

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 4; MDDGA4 253800 J:187144