Mouse Genome Informatics
cn
    Fktntm1Kcam/Fktntm1Kcam
Tg(CAG-cre/Esr1*)5Amc/?

involves: 129S/SvEv * C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
muscle
• iliopsoas muscle from mice treated with tamoxifen show indications of dystrophic disease
• variations in fiber size
• necrosis
• increase in centrally nucleated fibers

homeostasis/metabolism
• levels begin to rise at 14 weeks of age and are significantly elevated at 16-20 weeks after tamoxifen treatment at 10 weeks of age

growth/size/body
N
• normal body weight at 4- 20 weeks of age after tamoxifen treatment (J:187144)

behavior/neurological
N
• normal forelimb grip strength at 4-20 weeks of age after tampxifen treatment (J:187144)
• normal open field activity at 4-20 weeks of age after tampxifen treatment (J:187144)

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 4; MDDGA4 253800 J:187144