Phenotypes Associated with This Genotype

Genotype
MGI:5433620

• Allelic Composition: Emc10^{Gt(OST181617)Lex}/Emc10^{Gt(OST181617)Lex}
• Genetic Background: B6;129S5-Emc10^{Gt(OST181617)Lex}/Mmucd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

improved glucose tolerance ( J:171883 )

♂ • male homozygous mutant mice exhibit enhanced glucose tolerance when compared with sex-matched wild-type littermates

behavior/neurological

increased anxiety-related response ( J:171883 )

♀ • female homozygous mutant mice exhibit an increased anxiety-like response during open field testing

reproductive system

reduced male fertility ( J:171883 )

♂ • decreased fertility was noted in the single male mutant available for analysis