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Phenotypes Associated with This Genotype
Genotype
MGI:5433181
Allelic
Composition
Fezf2tm1.1Nses/Fezf2tm1.1Nses
Tbr1tm1Jlr/Tbr1tm1Jlr
Tg(Emx1-cre)#Ito/0
Tg(Mbp-MAPT/EGFP)#Eja/0
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fezf2tm1.1Nses mutation (1 available); any Fezf2 mutation (49 available)
Tbr1tm1Jlr mutation (1 available); any Tbr1 mutation (38 available)
Tg(Emx1-cre)#Ito mutation (0 available)
Tg(Mbp-MAPT/EGFP)#Eja mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Aberrant L6 projections to the brainstem in the Tbr1tm1Jlr/Tbr1tm1Jlr mice require Fezf2

nervous system
N
• unlike Tbr1tm1Jlr homozygotes, mice lack retrograde labeling of L5 and L6 projection neurons


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory