Phenotypes for Gli3 Tmem107 MGI:5433096 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Gli3^Xt-J/Gli3^Xt-J Tmem107^schlei/Tmem107^schlei
Genetic Background	involves: C3H/HeJ * C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli3^Xt-J mutation (3 available); any Gli3 mutation (84 available)
Tmem107^schlei mutation (0 available); any Tmem107 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal floor plate morphology ( J:186552 )

• absence of ventral cell types (V3) in the floor plate

• dorsal expansion of motor neuron progenitors and V2 interneuron progenitors observed in Tmem107^schlei homozygotes is exacerbated

nervous system

abnormal floor plate morphology ( J:186552 )

• absence of ventral cell types (V3) in the floor plate

• dorsal expansion of motor neuron progenitors and V2 interneuron progenitors observed in Tmem107^schlei homozygotes is exacerbated

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/28/2026 MGI 6.24