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Phenotypes Associated with This Genotype
Genotype
MGI:5433031
Allelic
Composition
Gabra1tm1.1Geh/Gabra1+
Genetic
Background
D2.129(Cg)-Gabra1tm1.1Geh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabra1tm1.1Geh mutation (0 available); any Gabra1 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• spike wave discharges associate with behavioral arrest and treatment with ethosuximide decreases the incidence of spike wave discharges
• Background Sensitivity: heterozygotes on a DBA/2J congenic background display an average of 19 spike wave discharge events per hour with no significant difference found between genders

nervous system
• spike wave discharges associate with behavioral arrest and treatment with ethosuximide decreases the incidence of spike wave discharges
• Background Sensitivity: heterozygotes on a DBA/2J congenic background display an average of 19 spike wave discharge events per hour with no significant difference found between genders


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory