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Phenotypes Associated with This Genotype
Genotype
MGI:5432918
Allelic
Composition		 Tespa1tm1Smoc/Tespa1tm1Smoc
Tg(TcraTcrb)425Cbn/0
Genetic
Background		 B6.Cg-Tespa1tm1Smoc Tg(TcraTcrb)425Cbn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tespa1tm1Smoc mutation (1 available); any Tespa1 mutation (31 available)
Tg(TcraTcrb)425Cbn mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell differentiation ( J:186446 )
• very few cells proceed to the CD4+ single positive stage

hematopoietic system
abnormal T cell differentiation ( J:186446 )
• very few cells proceed to the CD4+ single positive stage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory